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[3T12m-07(P-520)] Elucidation of the mechanism of saturated fatty acid-induced IRE1 activation by autophagy genes

Shunwei Ni1, Syunsuke Kasai1, Sosuke Akagi1, Hiroyuki Arai2, Nozomu Kono1,3, Zyunken Aoki1,4 (1.Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2.Laboratory of Microenvironmental and Metabolic Health Science, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, 3.AMED-CREST, 4.AMED-LEAP)

キーテクノロジー:CRISPR/Cas9, LC/MS, NGS

UPR、オートファジー、ゲノムワイドスクリーニング、飽和脂肪酸

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