[P-304] Biochemical studies of malate:quinone oxidoreductase from Toxoplasma gondii

^○R Acharjee¹, Talaam K. K.¹, Hartuti E. D.¹, Matsuo Y.², Sakura T.^2,3, Gloria B. M.¹, Hidano S.⁴, Kido Y.⁵, Mori M.⁶, Shiomi K.⁶, Sekijima M.⁷, Nozaki T.⁸, Umeda K.⁹, Kita Kiyoshi^5,6,10, Inaoka Daniel Ken^4,5,6 (1.Grad Sch Biomed Sci, Nagasaki Uni, 2.Sch Trop Med Glob Heal, Nagasaki Uni;, 3.Dept Mole Infect Dyn, Inst Trop Med, NEKKEN, Nagasaki Uni;, 4.Dept Immune Regu, The Res Cent Hepat Immunol, Nat Cent Glob Heal Med;, 5.Dept Para Res Cent Infectious Dis Sci, Grad Sch Med, Osaka City Uni;, 6.Grad Sch Infect Cont Sci, Kitasato Uni;, 7.Dept Adv Computa Drug Disc Unit, Tokyo Inst Tech;, 8.Dept Biomed Chem, Grad Sch Med, The Uni Tokyo;, 9.Res Unit Host Def, Nat Res Cent Proto Dis, Obihiro Uni Agri Vet Med, Hokkaido, 10.Dept Parasitol, Host-Def Biochem, NEKKEN, Nagasaki Uni.)

キーテクノロジー：Characterization of TgMQO

Toxoplasmosis、electron transport chain、malate:quinone oxidoreductase、enzyme inhibition、ferulenol