[P-304] Biochemical studies of malate:quinone oxidoreductase from Toxoplasma gondii

^○Acharjee R¹, K. K. Talaam¹, E. D. Hartuti¹, Y. Matsuo², T. Sakura^2,3, B. M. Gloria¹, S. Hidano⁴, Y. Kido⁵, M. Mori⁶, K. Shiomi⁶, M. Sekijima⁷, T. Nozaki⁸, K. Umeda⁹, Kiyoshi Kita^5,6,10, Daniel Ken Inaoka^4,5,6 (1.Grad Sch Biomed Sci, Nagasaki Uni, 2.Sch Trop Med Glob Heal, Nagasaki Uni;, 3.Dept Mole Infect Dyn, Inst Trop Med, NEKKEN, Nagasaki Uni;, 4.Dept Immune Regu, The Res Cent Hepat Immunol, Nat Cent Glob Heal Med;, 5.Dept Para Res Cent Infectious Dis Sci, Grad Sch Med, Osaka City Uni;, 6.Grad Sch Infect Cont Sci, Kitasato Uni;, 7.Dept Adv Computa Drug Disc Unit, Tokyo Inst Tech;, 8.Dept Biomed Chem, Grad Sch Med, The Uni Tokyo;, 9.Res Unit Host Def, Nat Res Cent Proto Dis, Obihiro Uni Agri Vet Med, Hokkaido, 10.Dept Parasitol, Host-Def Biochem, NEKKEN, Nagasaki Uni.)

キーテクノロジー：Characterization of TgMQO

Toxoplasmosis、electron transport chain、malate:quinone oxidoreductase、enzyme inhibition、ferulenol