[P-479(2T13a-04)] PACSIN1 is indispensable for amphisome-lysosome fusion during basal autophagy and lysophagy

^○Yukako Oe¹, Shin-ichiro Yoshimura², Yasuyoshi Kimura³, Kensuke Ikenaka³, Hideki Mochizuki³, Shuhei Nakamura^1,4,5, Tamotsu Yoshimori^1,4,6 (1.Department of Genetics, Graduate School of Medicine, Osaka University, 2.Department of Cell Biology, Graduate School of Medicine, Osaka University, 3.Department of Neurology, Graduate School of Medicine, Osaka University, 4.Laboratory of Intracellular Membrane Dynamics, Graduate School of Frontier Biosciences, Osaka University, 5.Institute for Advanced Co-Creation Studies, Osaka University, 6.Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University)

キーテクノロジー：電顕　線虫疾患モデル

オートファジー、アンフィソーム、リソソーム