The Japanese Biochemical Society

[P-493] Mechanism analysis of cytoplasmic vacuoles formation induced by CDK4/6 inhibitor abemaciclib

Hirotsugu Hino1, Yoshinori Tanaka2, Kosuke Takeya2, Naoharu Takano3, Masaki Hiramoto3, Shin Aizawa1, Keisuke Miyazawa3, Masumi Eto2, Shuichi Hirai1 (1.Div. of Anat. Sci., Dept. of Funct. Morpho., Nihon Univ. Sch. of Med., 2.Biochem. Unit, Fac. of Veterinary Med., Okayama Univ. of Sci., 3.Dept. of Biochem, Tokyo Med. Univ.)

キーテクノロジー:ライブセルイメージング

CDK4/6阻害薬、abemaciclib、リソソーム、細胞死、空胞形成

hino.hirotsugu@nihon-u.ac.jp

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