[P-503] Identification of a mutation responsible for cartilage degeneration in STR/ort, a mouse model developing spontaneous osteoarthritis

Lingyun Ma¹, Daichi Shigemizu^2,3, Hiroyuki Nakamura⁴, Kouichi Ozaki³, ^○Ken Watanabe^1,5 (1.Dept Musculoskeletal Disease, National Center for Geriatrics and Gerontology (NCGG), 2.Div Bioinformatics, NCGG, 3.Div Genome Medicine, NCGG, 4.Dept Oral and Maxillofacial Surgery, Ryukyu University Graduate School of Medical Science, 5.Div Bioresource Management, NCGG)

キーテクノロジー：WGS

変形性関節症、マウスモデル、ゲノム解析、フェロトーシス、炎症