The Japanese Biochemical Society

[P-590(1T15a-07)] Disruption of insulin receptor substrate-1 impairs growth and insulin function in rats

Yuka Toyoshima1,2, Katsuyuki Nakamura3, Shiho Takeuchi3, Reiko Tokita2, Yusuke Taguchi2, Naomi Teramoto3, Hidetoshi Sugihara3, Keitaro Yamanouchi3, Shiro Minami2 (1.Institute for Human Life Innovation, Ochanomizu University, 2.Department of Bioregulation, Institute for Advanced Medical Sciences, Nippon Medical School, 3.Department of Veterinary Physiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo)

キーテクノロジー:ゲノム編集

インスリン受容体基質、インスリン抵抗性、成長、CRISPR/Cas9

toyoshima.yuka@ocha.ac.jp

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