[P-610(2T14a-06)] Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway

^○Tra Thi Huong Dinh^1,2, Iseki Hiroyoshi³, Mizuno Seiya^1,2, Takahashi Satoru², Sugiyama Fumihiro^1,2 (1.Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, 2.Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, 3.International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan)

キーテクノロジー：genetically modified animal

Cables2、embryonic lethality、gastrulation、p53