The Japanese Biochemical Society

[P-743] Blocking the ARF6-AMAP1 pathway cooperatively improves anti-PD-1 immunotherapy for pancreatic cancer

Ari Hashimoto1, Haruka Handa1, Soichiro Hata1, Akio Tsutaho1,2, Takao Yoshida3, Satoshi Hirano2, Shigeru Hashimoto1,4, Hisataka Sabe1 (1.Dept. of Mol. Biol., Hokkaido Univ. Fac. of Med., 2.Dept. of Gastroent., Hokkaido Univ. Fac. of Med., 3.Res. Cent. of Onco., Ono Pharma.Co. Ltd., 4.Lab. of Immun. Reg., Immun. Front. Res. Cent.)

キーテクノロジー:免疫チェックポイント阻害の改善

ARF6、PDAC、eIF4A、KRAS、PD-1

ahashimo@med.hokudai.ac.jp

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