The Japanese Biochemical Society

[P-807] Hepatocyte-specific cFLIP deficiency exacerbates thioacetamide-induced chronic liver injury and fibrosis

Yuichi Tsuchiya1, Kenta Kobayashi1,2, Takao Seki1, Sachiko Komazawa1, Chiharu Nishiyama2, Tetuo Mikami3, Toru Imamura4, Minoru Tanaka5, Hiroyasu Nakano1 (1.Department of Biochemistry, Toho University School of Medicine, 2.Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, 3.Department of pathology, Toho University School of Medicine, 4.Imamura Laboratory for Biomedical Sciences, 5.Department of Regenerative Medicine, National Center for Global Health and Medicine)

キーテクノロジー:Conditional knockout mice

肝線維化、アポトーシス、チオアセトアミド、cFLIP、FGF18

tsuchiya@med.toho-u.ac.jp

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