[P-475] The protein N-terminal acetyltransferase A complex contributes to yeast mitophagy via promoting expression and phosphorylation of Atg32

^○Mitsutaka Kubota, Koji Okamoto (Graduate School of Frontier Biosciences, Osaka University)

The 94th Annual Meeting of JBS

[P-476(3T12m-04)] Atg15 in Saccharomyces cerevisiae consists of two functionally distinct domains

Eri Hirata^1,4, Kyo Shirai¹, Kosuke Sato¹, Fumito Kodama¹, ^○Kuninori Suzuki^1,2,3 (1.Department of Integrated Biosciences, Graduate School of Frontier Sciences, the University of Tokyo, 2.Life Science Data Research Center, Graduate School of Frontier Sciences, the University of Tokyo, 3.Collaborative Research Institute for Innovative Microbiology, the University of Tokyo, 4.Research Organization for Nano & Life Innovation, Waseda University, Tokyo, Japan)

The 94th Annual Meeting of JBS

[P-477] Analysis of the autophagy-mediated unconventional secretion mechanism of Parkinson's disease-associated protein DJ-1

^○Shoma Arizono, Yasuomi Urano, Biplab Kumar Dash, Noriko Noguchi (Sys. Life Sci. Lab., Grad. Sch. Of Life & Med. Sci., Doshisha Univ)

The 94th Annual Meeting of JBS

[P-478] Evolution of the autophagy-related ubiquitin-like conjugation systems in eukaryotes

^○Sidi Zhang, Euki Yazaki, Hirokazu Sakamoto, Hayashi Yamamoto, Noboru Mizushima (Department of Biochemistry and Molecular Biology, Graduate School of Medicine, The University of Tokyo)

The 94th Annual Meeting of JBS

[P-479(2T13a-04)] PACSIN1 is indispensable for amphisome-lysosome fusion during basal autophagy and lysophagy

^○Yukako Oe¹, Shin-ichiro Yoshimura², Yasuyoshi Kimura³, Kensuke Ikenaka³, Hideki Mochizuki³, Shuhei Nakamura^1,4,5, Tamotsu Yoshimori^1,4,6 (1.Department of Genetics, Graduate School of Medicine, Osaka University, 2.Department of Cell Biology, Graduate School of Medicine, Osaka University, 3.Department of Neurology, Graduate School of Medicine, Osaka University, 4.Laboratory of Intracellular Membrane Dynamics, Graduate School of Frontier Biosciences, Osaka University, 5.Institute for Advanced Co-Creation Studies, Osaka University, 6.Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University)

The 94th Annual Meeting of JBS

[P-480] Campylobacter jejuni recruits LC3 to bacterial entry site via Rac1 signaling pathway in the Host Epithelial Cells

^○Shiho Fukushima¹, Takaaki Shimohata^1,2, Takashi Uebanso¹, Kazuaki Mawatari¹, Akira Takahashi¹ (1.Department of Preventive Environment and Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School, 2.Department of Marine Bioresources, Fukui Prefectural University)

The 94th Annual Meeting of JBS

[P-481] Azithromycin enhanced DNA-damaging drug-induced cell death by suppressing lysophagy and promoting lysosomal membrane permeability.

Kazutoshi Toriyama¹, ^○Naoharu Takano², Hiroko Kokuba³, Hiromi Kazama², Shota Moriya², Masaki Hiramoto², Shinji Abe¹, Keisuke Miyazawa² (1.Dept. of Resp. Med., Tokyo Med. Univ., 2.Dept. of Biochem., Tokyo Med. Univ., 3.Lab. of Electron Microscopy, Tokyo Med. Univ.)

The 94th Annual Meeting of JBS

[P-482] Isoliquiritigenin induces non-apoptotic cell death by inducing endoplasmic reticulum stress and down-regulation of survivin expression in human melanoma G361 cells

^○Akihisa Abe, Shota Moriya, Hiromi Kazama (Department of Biochemistry, Tokyo Medical University)

The 94th Annual Meeting of JBS

[P-483(2T13a-08)] p300-mediated acetylation promotes MCL1 stabilization and tumorigenesis

^○Kouhei Shimizu¹, Min Gi^2,3, Shugo Suzuki², Fuminori Tokunaga¹, Hiroyuki Inuzuka⁴, Wenyi Wei⁴ (1.Department of Pathobiochemistry, Graduate School of Medicine, Osaka City University, 2.Department of Molecular Pathology, Graduate School of Medicine, Osaka City University, 3.Department of Environmental Risk Assessment, Graduate School of Medicine, Osaka City University, 4.Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School)

The 94th Annual Meeting of JBS

[P-484(2T13a-12)] Discovery of FGF21 as a "kick-me-out" signal in cell competition

^○Motoyuki Ogawa, Isao Naguro, Hidenori Ichijo (Cell Signaling, Grad. Sch. Pharmaceut. Sci., Univ. of Tokyo)

The 94th Annual Meeting of JBS