[P-165] Oleic acid promotes cell proliferation through regulation of glutaminolysis in RMG-1 ovarian cancer cells

^○Takeru Tamaki, Nobuyuki Fukushima (Kindai Univ. Graduate School of Science and Engineering)

The 94th Annual Meeting of JBS

[P-166(3T13m-02)] Localization analysis of PI(4,5)P₂ in the yeast plasma membrane using the freeze-fracture EM method to elucidate the regulatory mechanism of the PI(4,5)P₂ production.

^○Yuna Kurokawa, Rikako Konishi, Kanna Tomioku, Akikazu Fujita (Department of Molecular and Cell Biology and Biochemistry, Basic Veterinary Science, Faculty of Veterinary Medicine, Kagoshima University)

The 94th Annual Meeting of JBS

[P-167] Homology modeling appears binding pocket of lysophosphatidylcholine acyltransferase 2 to catch the substrate.

^○Fumie Hamano^1,2, Kazuaki Matoba³, Tomomi Yoshida-Hashidate², Tomoyuki Suzuki², Yoshihiro Kita¹, Nobuo Noda³, Hideo Shindou², Takao Shimizu² (1.Life Sci. Core Facility, Grad. Sch. of Med., Univ. of Tokyo, 2.Dept. of Lipid Signaling, National Center for Global Health and Medicine, 3.Inst. of Microbial Chem.)

The 94th Annual Meeting of JBS

[P-168(2T14m-04)] Group XIIA secreted phospholipase A₂-driven lipid metabolism promotes Th17 cell induction leading to psoriasis

^○Chika Mochizuki¹, Yoshitaka Taketomi¹, Takahiro Nakazima², Yusuke Endo², Junken Aoki³, Makoto Murakami^1,4 (1.DBIM, Grad. Sch. Med., UTokyo, 2.Lab. Med. Omics Res., Kazusa DNA Res. Inst, 3.Lab. Health Chem., Grad. Sch. Pharm. Sci., UTokyo, 4.AMED-CREST)

The 94th Annual Meeting of JBS

[P-169(3T13m-05)] Functional roles of class II PI3-kinase in vascular smooth muscle contraction

^○Kazuaki Yoshioka¹, Shahidul Islam¹, Sho Aki¹, Kazuhiro Ishimaru¹, Noriko Takuwa^1,2, Yoh Takuwa¹ (1.Department of Physiology, Kanzawa University School of Medical Sciences, 2.Department of Health Science, Ishikawa Prefectural Nursing University)

The 94th Annual Meeting of JBS

[P-170] Photocontrol the HVR domain in the small G-protein Ras GTPase activity using azobenzene derivatives

^○Rufiat Nahar, Shinsaku Maruta (Soka University)

The 94th Annual Meeting of JBS

[P-171(3T14m-11)] Co-crystal structure analysis of Ferulenol derivatives in complex with human dihydroorotate dehydrogenase: a therapeutic target for cancer cells living under tumor microenvironment

^○Tagod Mohammed S. O.¹, Takaya Takaya^1,2, Eri Amalia³, Takahiro Sasagawa³, Osumi Yukiko⁴, Matsui Hiroki⁴, Masuda Ayuna⁴, Yukiko Miyazaki¹, Tomoo Shiba⁴, Hiroyuki Saimoto⁵, Kiyoshi Kita^2,3,6, Daniel Ken Inaoka^1,2,3 (1.Department of Molecular Infection Dynamics, NEKKEN, Nagasaki University, 2.School of Tropical Medicine and Global Health, 3.Department of Biomedical Chemistry, The University of Tokyo, 4.Department of Applied Biology, Kyoto Institute of Technology, 5.Department of Chemistry and Biotechnology, Tottori University, 6.Department of Host-Defense Biochemistry, NEKKEN)

The 94th Annual Meeting of JBS

[P-172] Structural and biochemical characterizations of major pilin protein CppA, minor pili protein CppB, and sortase C from Clostridium perfringens

^○Shigehiro Kamitori¹, Mitsugu Yamada², Takuya Ishida², Hiroshi Sekiya³, Eiji Tamai^1,3 (1.Life Science Research Center and Faculty of Medicine, Kagawa University, 2.Japan Aerospace Exploration Agency (JAXA), 3.College of Pharmaceutical Science, Matsuyama University)

The 94th Annual Meeting of JBS

[P-173] Binding of Grb2 to CD28 cytoplasmic region and its contribution of two SH3 domains and dimerization

^○Saki Ochi¹, Momoka Iiyama², Masayuki Oda^1,2 (1.Faculty Life Environ. Sci., Kyoto Pref. Univ., 2.Grad. Sch. Life Environ. Sci., Kyoto Pref. Univ.)

The 94th Annual Meeting of JBS

[P-174] Mutational effects of Cys residues of PI3K cSH2 on stability and binding to cytoplasmic regions of receptors

^○Momoka Iiyama¹, Nobutaka Numoto², Nobutoshi Ito², Masayuki Oda¹ (1.Grad. Sch. Life Environ. Sci., Kyoto Pref. Univ., 2.Med. Res. Inst., Tokyo Med. Dent. Univ.)

The 94th Annual Meeting of JBS