[P-185] Elucidation of the structure-function relationship of peptidyl arginine deiminase type 3

^○Mizuki Sawata¹, Hiroki Shima², Toshitaka Matsui³, Kazumasa Funabashi¹, Hidenari Takahara^4,5, Kazutaka Murayama², Kazuhiko Igarashi², Masaki Unno^1,5 (1.Graduate School of Science and Engineering, Ibaraki University, 2.Graduate School of Medicine, Tohoku University, 3.Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 4.College of Agriculture, Ibaraki University, 5.Frontier Research Center for Applied Atomic Sciences, Ibaraki University)

The 94th Annual Meeting of JBS

[P-186(1T15m-07)] Cryo-EM structure of the human MT1-Gi signaling complex

^○Hiroyuki H Okamoto¹, Hirotake Miyauchi¹, Asuka Inoue², Francesco Raimondi³, Hirokazu Tsujimoto⁴, Tsukasa Kusakizako¹, Wataru Shihoya¹, Keitaro Yamashita^1,5, Ryoji Suno⁶, Takuya Kobayashi⁶, So Iwata^4,7, Tomohiro Nishizawa⁸, Osamu Nureki¹ (1.Graduate School of Science, The University of Tokyo, 2.Graduate School of Pharmaceutical Sciences, Tohoku University, 3.Laboratorio di Biologia Bio@SNS, Scuola Normale Superiore, Piazza dei Cavalieri, 4.Department of Cell Biology, Graduate School of Medicine, Kyoto University, 5.MRC Laboratory of Molecular Biology, 6.Department of Medical Chemistry, Kansai Medical University, 7.RIKEN SPring-8 Center, 8.Graduate School of Medical Life Science, Yokohama City University)

The 94th Annual Meeting of JBS

[P-187] Conformational changes in N-terminal region of DGKα that regulates the enzyme activation

^○Daisuke Takahashi¹, Kento Yonezawa², Yuki Okizaki¹, Atsushi Shimada³, Jose Caaveiro¹, Yoshito Abe¹, Tadashi Ueda¹, Nobutaka Shimizu², Fumio Sakane⁴ (1.Graduate School of Pharmaceutical Sciences, Kyushu University, 2.Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), 3.Medical Institute of Bioregulation, Kyushu University, 4.Graduate School of Science, Chiba University)

The 94th Annual Meeting of JBS

[P-188] Comparison of the sulfur-carrying states of SufE and SufU involved in iron-sulfur cluster biogenesis

^○Chisato Maki, Suguru Muroga, Takuya Terahata, Yukino Shimada, Kouhei Kunichika, Ryosuke Nakamura, Takashi Fujishiro, Yasuhiro Takahashi (Department of Biochemistry and Molecular Biology, Graduate School of Science and Engineering, Saitama University)

The 94th Annual Meeting of JBS

[P-189] Unusual quaternary structure of a homodimeric synergistic toxin from mamba snake venom

^○Narumi Aoki-Shioi^1,2, Isao Kuraoka¹, R.Manjunatha Kin² (1.Dep. Sci, Fukuoka University, 2.Dep.Bio.Sci, National University of Singapore)

The 94th Annual Meeting of JBS

[P-190(1T15m-08)] Structures and roles of cholesterol molecules bound to the multidrug efflux transporter P-glycoprotein

^○Norie Hamaguchi¹, Naruhiko Adachi², toshio moriya², masato kawasaki², sisi chin¹, kenji Yasuda¹, toshiya senda², satoshi ogasawara¹, takeshi murata¹ (1.Dept of chem, Grad Sch of sci, Chiba Univ, 2.IMSS, KEK)

The 94th Annual Meeting of JBS

[P-191] Specific plasmid degradation by snake venom Phosphodiesterase

^○Ryosuke Shikasho, Yoshifumi Zaitsu, Isao Kuraoka, Narumi Aoki-Shioi (The department of chemistry, Faculty of science, Fukuoka university)

The 94th Annual Meeting of JBS

[P-192] Structural basis for specific recognition of K48-linked ubiquitin chains by UBA domain of RAD23A

^○Yusuke Sato^1,2, Aya Urishima², Tomoya Hino^1,2, Shingo Nagano^1,2 (1.GSC Center, Tottori Univ., 2.Dept. of Engineering, Tottori Univ.)

The 94th Annual Meeting of JBS

[P-193] Development of anti fusion partner protein monoclonal antibodies for GPCR structural analysis

^○Masaya Tsurumachi, Fuhito Nakagawa, Sisi Chin, Takeshi Murata, Satoshi Ogasawara (Graduate school of Science ,Chiba University)

The 94th Annual Meeting of JBS

[P-194(1T15m-11)] Binding mode and structural changes of beta-arrestin to vasopressin V2 receptors

^○Ritsuki Kuramoto, Tatsuya Ikuta, Kouki Kawakami, Asuka Inoue (Graduate School of Pharmaceutical Sciences, Tohoku University)

The 94th Annual Meeting of JBS