[1T15m-10(P-207)] Structural insights into biased agonism in sphingosine-1-phosphate receptors

^○Shintaro Maeda^1,2, Yuki Shiimura^3,4, Hidetsugu Asada⁴, Kunio Hirata⁵, Luo Fangjia⁵, Eriko Nango^5,6, Asuka Inoue⁷, Junken Aoki⁸, So Iwata^4,5, Masatoshi Hagiwara¹ (1.Department of Anatomy and Developmental Biology, Graduate school of Medicine, Kyoto University Japan, 2.Department of Drug Discovery Medicine, Graduate school of Medicine, Kyoto University Japan, 3.Institute of Life Science, Kurume University, Kurume, Japan, 4.Department of Cell Biology, Graduate school of Medicine, Kyoto University Japan, 5.RIKEN SPring-8, 6.Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Japan, 7.Laboratory of Molecular and Cellular Biolchemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan, 8.Department of Health Chemistry, Graduate School of Pharmaceutical Scienecs, The University of Tokyo)

The 94th Annual Meeting of JBS |Wed. Nov 3, 2021 10:30 AM - 10:40 AM

[1T15m-11(P-194)] Binding mode and structural changes of beta-arrestin to vasopressin V2 receptors

^○Ritsuki Kuramoto, Tatsuya Ikuta, Kouki Kawakami, Asuka Inoue (Graduate School of Pharmaceutical Sciences, Tohoku University)

The 94th Annual Meeting of JBS |Wed. Nov 3, 2021 10:40 AM - 10:50 AM

[1T15m-12(P-197)] Conformational changes neighboring the GTP-binding site of small GTPase Ras upon GTP hydrolysis process.

^○Maho Saeki¹, Yoshiteru Makino², Takashi Kawamura³, Eriko Nango⁴, Takashi Kumasaka³, Fumi Shima¹ (1.Grad. Sch. Sci. Tec. Innov., Kobe Univ., 2.Grad. Sch. Med., Kobe Univ., 3.SPring-8, JASRI., 4.IMRAM., Tohoku Univ.)

The 94th Annual Meeting of JBS |Wed. Nov 3, 2021 10:50 AM - 11:00 AM

[1T13a-01(P-300)] Reaction mechanism analysis based on crystal structure of L-methionine decarboxylase from Streptomyces

^○Atsushi Okawa¹, Tomoaki Inoue², Yuki Onoue², Tomoo Shiba², Junko Inagaki³, Takashi Tamura¹, Kenji Inagaki¹ (1.Grad. Sch. Environ. Life Sci., Okayama Univ., 2.Grad. Sch. Sci. Technol., Kyoto Inst. Technol., 3.Grad. Sch. Med. Dent. Pharm. Sci., Okayama Univ.)

The 94th Annual Meeting of JBS |Wed. Nov 3, 2021 2:50 PM - 3:00 PM

[1T13a-02(P-302)] Analysis of archaeal cis-prenyltransferase via fusion of hetero-subunits

^○Arisa Nagasaka, Kitty Sompiyachoke, Tohru Yoshimura, Hisashi Hemmi (Department of Applied Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University)

The 94th Annual Meeting of JBS |Wed. Nov 3, 2021 3:00 PM - 3:10 PM

[1T13a-03(P-309)] Heat-induced activation and conformational changes of homoserine dehydrogenase from a hyperthermophilic archaeon Sulfurisphaera tokodaii

^○Tatsuya Kubota¹, Erika Kurihara², Masaru Goto², Toshihisa Ohshima³, Kazuaki Yoshimune¹ (1.Graduate School of Industrial Science and Technology, Nihon university, 2.Graduate School of Science, Toho University, 3.Department of Biomedical Engineering, Osaka Institute of Technology)

The 94th Annual Meeting of JBS |Wed. Nov 3, 2021 3:10 PM - 3:20 PM

[1T13a-04(P-311)] Dissection and reconstitution of the membrane-bound aldehyde dehydrogenase complex of acetic acid bacteria

^○Toshiharu Yakushi^1,2,3, Roni Miah², Riho Izumi³, Takeru Murate², Naoya Kataoka^1,2,3, Kazunobu Matsushita^1,2,3 (1.RCTMR, Yamaguchi University, 2.Graduate School of Sciences and Technology for Innovation, Yamaguchi University, 3.Faculty of Agriculture, Yamaguchi University)

The 94th Annual Meeting of JBS |Wed. Nov 3, 2021 3:20 PM - 3:30 PM

[1T13a-05(P-303)] Identification of 3,4-dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine derivatives as novel selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase

^○Hartuti Endah Dwi^1,2,3, Takaya Sakura^4,5, Mohammed S. O. Tagod⁵, Eri Yoshida⁴, Xinying Wang^5,6, Kota Mochizuki⁷, Rajib Acharjee^1,2, Fuyuki Tokumasu⁸, Mihoko Mori⁹, Danang Waluyo³, Kazuro Shiomi⁹, Tomoyoshi Nozaki⁶, Shinjiro Hamano^1,2 (1.Program for Nurturing Global Leaders in Tropical and Emerging Communicable Disease, Nagasaki University, 2.Department of Parasitology, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 3.Laboratory for Biotechnology, Agency for the Assessment and Application of Technology, Indonesia, 4.Department of Molecular Infection Dynamics, NEKKEN, Nagasaki University, 5.School of Tropical Medicine and Global Health, Nagasaki University, 6.Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7.Department of Immunogenetics, NEKKEN, Nagasaki University, 8.Department of Cellular Architecture Studies, NEKKEN, Nagasaki University, 9.Graduate School of Infection Control Sciences, Kitasato University, 10.Department of Host-Defense Biochemistry, NEKKEN, Nagasaki University)

The 94th Annual Meeting of JBS |Wed. Nov 3, 2021 3:30 PM - 3:40 PM

[1T13a-06(P-315)] Involvement of periplasmic multiheme-containing selenoprotein in polysulfide reduction in Geobacter sulfurreducens

^○Shintaro Asaoka¹, Yukiko Izu¹, Riku Aono¹, Masao Inoue^1,2, Hisaaki Mihara¹ (1.College of Life Sciences, Ritsumeikan University, 2.Ritsumeikan Global Innovation Research Organization)

The 94th Annual Meeting of JBS |Wed. Nov 3, 2021 3:40 PM - 3:50 PM

[1T13a-07(P-328)] Identification of vitamin B₆ phosphatase in Escherichia coli

^○Hinano Matsuo, Tomokazu Ito, Hisashi Hemmi, Tohru Yoshimura (Nagoya University Graduate School of Bioagricultural Sciences)

The 94th Annual Meeting of JBS |Wed. Nov 3, 2021 3:50 PM - 4:00 PM