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[1T02a-07(2P-003)] The role of glycosylation in the contact activation of blood coagulation factor XII

Maho Saita1, Sumika Nakamura1, Marina Chikaraishi2, Takao Arimori3, Junichi Takagi3, Tetsuya Okajima4, Hideyuki Takeuchi5, Kyoko Kojima-Aikawa1 (1.Div. of Advanced Sciences, Grad. Sch. of Humanities and Sciences, Ochanomizu Univ., 2.Dept. of Chemistry, Fac. of Science, Ochanomizu Univ., 3.Inst. Protein Research, Osaka Univ., 4.Dept. of Molecular Biochemistry, Nagoya Univ. Grad. Sch. of Medicine, 5.Dept. of Biochemistry, Sch. of Pharmaceutical Sciences, Univ. of Shizuoka)

キーテクノロジー:真核細胞を用いたタンパク質発現

血液凝固第XII因子、セリンプロテアーゼ、O-フコース修飾、ムチン型O-糖鎖修飾

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