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[1T08a-07(3P-138)] Inhibition of xCT,cystine/glutamate transporter, supresses chronic inflammation in a mouse model of inflammatory bowel disease

Hideya Iwaki1, Hiroki Sekine1, Shohei Murakami1, Nobufumi Kato3, Hiroshi Kitamura4, Fan-Yan WE5, Shinji Fukuda6, Tomoyoshi Soga6, Yoichi Kakuta2, Atsushi Masamune2, Hozumi Motohashi1 (1.Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, 2.Division of Gastroenterology, Tohoku University, 3.Division of Advanced Surgical Science and Technology, Tohoku University, 4.Division of Microbiology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, 5.Department of Modomics Biology and Medicine, Institute of Development, Aging and Cancer, Tohoku University, 6.Institute for Advanced Biosciences, Keio University)

キーテクノロジー:オルガノイド

膜トランスポーター、慢性炎症、炎症性腸疾患、オルガノイド

hideya.iwaki.a2@tohoku.ac.jp

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