Effect of a lactic acid bacteria-generated polyunsaturated fatty acid metabolite 10-oxo-cis-12-octadecenoic acid (KetoA) on exhausted CD8+ T cells and antitumor activity.

Yuki Ikeda

2:20 PM - 2:30 PM

[1T13a-07（2P-339）] Effect of a lactic acid bacteria-generated polyunsaturated fatty acid metabolite 10-oxo-cis-12-octadecenoic acid (KetoA) on exhausted CD8+ T cells and antitumor activity.

^〇Yuki Ikeda¹, Naoki Kodama¹, Takuya Yashiro¹, Masakazu Hachisu¹, Shigenobu Kishino², Jun Ogawa², Chiharu Nishiyama¹ (1.Dept. Biol. Sci. Technol., Tokyo Univ. Sci., 2.Grad. Sch. Agriculture, Kyoto Univ.)

キーテクノロジー：フローサイトメトリー

多価不飽和脂肪酸、免疫チェックポイント阻害薬、ミトコンドリア、CD8⁺T細胞機能回復、KetoA

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The 95th Annual Meeting of the Japanese Biochemical Society

[1T13a-07（2P-339）] Effect of a lactic acid bacteria-generated polyunsaturated fatty acid metabolite 10-oxo-cis-12-octadecenoic acid (KetoA) on exhausted CD8+ T cells and antitumor activity.

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