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[1T18e-03(3P-378)] An exploratory study of inhibitors that target YAP-TEAD interaction in the Hippo pathway

Saaya Sekine1,2, Shohei Takase1, Kota Noritsugu1, Rumi Kurokawa2, Yasue Ichikawa2, Kenji Ogawa2,3, Ken Matsumoto2, Hiroyuki Osada2, Minoru Yoshida2,4, Akihiro Ito1,2 (1.Sch. of Life Sci., Tokyo Univ. of Pharm. and Life Sci., 2.RIKEN CSRS, 3.Col. of Biores. Sci., Nihon Univ., 4.Dept. Biotechnol. and CRIIM, Univ. Tokyo)

キーテクノロジー:ハイスループットスクリーニング

Hippo経路、YAP、TEAD、化合物スクリーニング、shRNAスクリーニング

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