[2P-182] A novel mouse line systemically expressing an autophagic flux reporter revealed autophagy suppression in pathological conditions.

^〇Yuki Kanda¹, Tomoya Eguchi¹, Hideaki Morishita^1,2, Yutaro Hama^1,3, Manabu Abe⁴, Kenji Sakimura⁴, Noboru Mizushima¹ (1.Dept. of Biochemistry and Molecular Biology, Graduate School of Medicine, The University of Tokyo, 2.Dept. of Physiology, Juntendo University Graduate School of Medicine, 3.Division of Biological Molecular Mechanisms, Institute for Genetic Medicine, Hokkaido University, 4.Dept. of Cellular Neurobiology, Brain Research Institute, Niigata University)

キーテクノロジー：ノックインマウス

オートファジー、レポーター、マウス