The Japanese Biochemical Society

[2P-182] A novel mouse line systemically expressing an autophagic flux reporter revealed autophagy suppression in pathological conditions.

Yuki Kanda1, Tomoya Eguchi1, Hideaki Morishita1,2, Yutaro Hama1,3, Manabu Abe4, Kenji Sakimura4, Noboru Mizushima1 (1.Dept. of Biochemistry and Molecular Biology, Graduate School of Medicine, The University of Tokyo, 2.Dept. of Physiology, Juntendo University Graduate School of Medicine, 3.Division of Biological Molecular Mechanisms, Institute for Genetic Medicine, Hokkaido University, 4.Dept. of Cellular Neurobiology, Brain Research Institute, Niigata University)

キーテクノロジー:ノックインマウス

オートファジー、レポーター、マウス

kan-yuki@m.u-tokyo.ac.jp

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