[2P-335] Molecular mechanism of schizophrenia-like behavioral deficits induced by methylglyoxal detoxification impairments

^〇Kazuya Toriumi¹, Shin Koike², Takashi Dan³, Kazuhiro Suzuki^1,4, Mitsuhiro Miyashita^1,5, Yasue Horiuchi¹, Yuki Ogasawara², Toshio Miyata³, Masanari Itokawa¹, Makoto Arai¹ (1.Schizophrenia Research Project, Tokyo Metropolitan Institute of Medical Science, 2.Department of Analytical Biochemistry, Meiji Pharmaceutical University, 3.Division of Molecular Medicine and Therapy, Tohoku University Graduate School of Medicine, 4.Department of Psychiatry, Graduate School of Medicine, Shinshu University, 5.Research Center for Social Science & Medicine, Tokyo Metropolitan Institute of Medical Science)

キーテクノロジー：RNA-seq

統合失調症、メチルグリオキサール、終末糖化産物、酸化ストレス、ビタミンB6