The Japanese Biochemical Society

[2P-365] A novel tetravalent peptide suppresses both production and aggregation of Amyloid β.

Waka Sato1,2, Miho Takahashi1, Takuya Murata3, Naoko Tate3, Hina Uchiyama4, Takashi Saito5, Takaomi Saido6, Satoru Funamoto4, Kiyotaka Nishikawa1 (1.Doshisha University, Grad.School of Life and Medical Sciences, Molecular Life Sciences, 2.The University of Tokyo, Grad.School of Pharmaceutical Sciences, , 3.Teikyo University, Faculty of Pharma-Science, Biomolecular Chemistry, 4.Doshisha University, Grad.School of Life and Medical Sciences, Neuropathology, 5.Nagoya City University, Grad.School of Medical Sciences, Neurocognitive Science, 6.RIKEN Center for Brain Science, Laboratory for Proteolytic Neuroscience)

キーテクノロジー:多価型ペプチドライブラリー法

アルツハイマー病、APP、Amyloid β、β-セクレターゼ、線維形成・凝集

wasato@g.ecc.u-tokyo.ac.jp

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