p53 simultaneously induces cytotoxic lysosomal membrane permeabilization and cytoprotective autophagy in response to DNA-damaging anticancer drugs.

Gai Yamashita

[2P-407（2T-17e-L06）] p53 simultaneously induces cytotoxic lysosomal membrane permeabilization and cytoprotective autophagy in response to DNA-damaging anticancer drugs.

Gai Yamashita¹, ^〇Takano Naoharu², Kazama Hiromi², Tsukahara Kiyoaki¹, Miyazawa Keisuke², , ², , (1.Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University Hospital, 2.Department of Biochemistry, Tokyo Medical University)

キーテクノロジー：LMP assay

autophagy、lysosome、LMP、p53

ntakano@tokyo-med.ac.jp

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The 95th Annual Meeting of the Japanese Biochemical Society

[2P-407（2T-17e-L06）] p53 simultaneously induces cytotoxic lysosomal membrane permeabilization and cytoprotective autophagy in response to DNA-damaging anticancer drugs.

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