The Japanese Biochemical Society

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[2T14a-01(1P-288)] SMG6 Regulates DNA Damage and Cell Survival in Hippo Pathway Kinase LATS2-Inactivated Malignant Mesothelioma

Koya Suzuki1,2,3, Ryota Yamagishi4, Satomi Mukai5, Tomohiro Akashi6, Ichiro Takeuchi7, Kenji Kadomatsu8, Tohru Maeda9, Hiroshi Murakami10, Takashi Miida2, Yoshitaka Sekido5, Yuko Murakami-Tonami1,2 (1.Mol. Cancer Genet. Lab., Tokyo Univ. Tech. Grad Sch. Bionics, 2.Dept. Clin. Lab. Med., Juntendo Univ. Grad. Sch. Med., 3.Adv. Comp. Res. Org., Teikyo Univ., 4.Dept. Pathophys., Osaka Met. Univ. Grad. Sch. Med, 5.Div. Cancer. Biol., Aichi Cancer Ctr. Res. Inst., 6.Dept. Integrative Cellular Inform., Nagoya Univ. Grad. Sch. Med., 7.Mech. Sys. Eng., Nagoya Univ. Grad. Sch. Eng., 8.Dept. Biochem., Nagoya Univ. Grad. Sch. Med., 9.Col. Pharm., Kinjo Gakuin Univ., 10.Dept. Biol. Sci., Fac. Sci. Eng., Chuo Univ.)

キーテクノロジー:担がんマウス

悪性中皮腫、合成致死、Hippo経路、テロメラーゼ逆転写酵素

suzuki.kouya.iw@teikyo-u.ac.jp

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