The Japanese Biochemical Society

[3P-143] Functional analysis of the tight junction protein ZO-1 by inserting single mutations predicted by structure-based method

Sachiko Fujiwara1,2, Takeshi Tenno3, Hidekazu Hiroaki3, Mikio Furuse1,2 (1.Division of Cell Structure, National Institute for Physiological Sciences, 2.School of Life Science, SOKENDAI, 3.Division of Structural Biology, Graduate School of Pharmaceutical Sciences, Nagoya University)

キーテクノロジー:立体構造に基づく点変異導入

上皮細胞、細胞間接着、タイトジャンクション

sfujiwar@nips.ac.jp

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