The Japanese Biochemical Society

[3P-350] New posttranslational modification of α-synuclein by tyrosine hydroxylase is a potential pathogenesis of Parkinson's disease.

Sakiko Matsumoto1, Mingyue Jin1, Takashi Ayaki2, Hodaka Yamakado2, Tomoyuki Taguchi2, Natsuko Togawa2, Ayumu Konno3, Hirokazu Hirai3, Ryosuke Takahashi2, Toshifumi Takao4, Shinji Hirotsune1 (1.Department of Genetic Disease Research, Osaka Metropolitan University Graduate School of Medicine, 2.Department of Neurology, Kyoto University Graduate School of Medicine, 3.Department of Neurophysiology & Neural Repair, Gunma University Graduate School of Medicine, 4.Laboratory of Protein Profiling and Functional Proteomics, Osaka University Institute for Protein Research)

キーテクノロジー:質量分析、HPLC、免疫染色

神経変性、ドーパミン作動性神経

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