The Japanese Biochemical Society

[3P-409(2T-17e-L09)] Heme deficiency in pancreatic islets caused impaired insulin secretion due to mitochondrial dysfunction

Kazuya Takeda1,2, van Wijk Koen1,2, Kimura Tomohiro1,2, Okano Satoshi1,2, Saitoh Shinichi2,3, Kodama Ken4, Tanaka Tohru2,3, Nakajima Osamu1,2, (1.Department of Functional Genomics, Yamagata University School of Medicine , 2.Research Center for Molecular Genetics, Institute for Promotion of Medical Science Research, Yamagata University Faculty of Medicine, 3.Department of Immunology, Yamagata University School of Medicine, 4.neopharma Japan, Co., Ltd.)

キーテクノロジー:遺伝子破壊マウス

ヘム、インスリン分泌、分離膵島、5-アミノレブリン酸、ミトコンドリア

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