A cardiac glycoside, periplocin suppresses the unfolded protein responses and exhibits anticancer activity against multiple myeloma.

Chisane Kujirai

9:10 AM - 9:20 AM

[3T17m-02（1P-200）] A cardiac glycoside, periplocin suppresses the unfolded protein responses and exhibits anticancer activity against multiple myeloma.

^〇Chisane Kujirai¹, Muneshige Tokugawa¹, Yasumichi Inoue¹, Kan'ichiro Ishiuchi², Michiyo Matsuno³, Masaki Ri⁴, Chiharu Miyajima¹, Shinsuke Iida⁴, Hajime Mizukami¹, Toshiaki Makino², Hidetoshi Hayashi¹ (1.Department of Cell Signaling, Graduate School of Pharmaceutical Sciences, Nagoya City University, 2.Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3.The Kochi Prefectural Makino Botanical Garden, 4.Department of Hematology and Oncology, Graduate School of Medical Sciences, Nagoya City University)

キーテクノロジー：小胞体ストレス応答

小胞体ストレス応答、XBP-1、強心配糖体、多発性骨髄腫

c212716@ed.nagoya-cu.ac.jp

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The 95th Annual Meeting of the Japanese Biochemical Society

[3T17m-02（1P-200）] A cardiac glycoside, periplocin suppresses the unfolded protein responses and exhibits anticancer activity against multiple myeloma.

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