[3P-132] Regulation of immune response via TCR signaling by supersulfides targeting CD3 chain

^〇Masanobu Morita¹, Mitsuhiro Yamada², Yusaku Sasaki², Tomoaki Ida¹, Tetsuro Matsunaga¹, Tsuyoshi Takata¹, Satoshi Watanabe³, Kenji Inaba³, Naoto Ishii⁴, Hisatoshi Sugiura², Hozumi Motohashi⁵ (1.Dept. Environ. Med. Mol. Toxicol., Tohoku Univ., Grad. Sch. of Med., 2.Dept. Respir. Med., Tohoku Univ., Grad. Sch. of Med., 3.Institute of Multidisciplinary Research for Advanced Materials, Tohoku Univ., 4.Dept. Microbiol. Immunol., Tohoku Univ., Grad. Sch. of Med. , 5.Dept. Gene Exp. Reg., IDAC, Tohoku Univ.)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-133（3T18m-06）] Function of mitochondrial sulfur metabolites in erythroid differentiation

^〇Eunkyu Sung¹, Shohei Murakami¹, Tomoaki Ida², Masanobu Morita², Takaaki Akaike², Hozumi Motohashi¹ (1.Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, 2.Department of Environmental Medicine and Molecular Toxicology, Tohoku University )

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-134（3T18m-08）] Analysis of reactivity of a glycosylated glutathione derivative, which is not degraded by gamma-glutamyltranspeptidase, with chemicals causing contact dermatitis

^〇Akiko Kanamori^1,2,3,5, Rihana Okabe³, Nana Egawa², Suyako Yamasaki², Yusuke Tomabechi^3,4 (1.Dept. of Bioeng., Sch. of Engineering, Tokai Univ., 2.Dept. of Appl. Biochem., Sch. of Engineering, Tokai Univ., 3.Course of Appl. Sci., Grad. Sch. of Engineering, Tokai Univ., 4.Dept. of Appl. Chem., Sch. of Engineering, Tokai Univ., 5. Inst. Adv. Biosci., Tokai Univ.)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-135] Supersulfide biosynthesis pathway mediated by aminoacyl-tRNA synthetase

^〇Minkyung Jung¹, Tomoaki Ida¹, Akira Nishimura², Tetsuro Matsunaga¹, Masanobu Morita¹, Tsuyoshi Takata¹, Hozumi Motohashi³, Takaaki Akaike¹ (1.Dept. Environ. Med. Mol. Toxicol., Tohoku Univ., Grad. Sch. of Med., 2.Grad. Sch. Biol. Sci. NAIST, 3.Dept. Gene Exp. Reg., IDAC, Tohoku Univ.)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-136] Down-regulation of ROS-generating NADPH oxidase 4 (NOX4) expression in hemangioendothelioma

^〇Kei Miyano^1,2 (1.Dept. Biochem., Kawasaki Med. Sch., 2.Dept. Natural Sci., Kawasaki Med. Sch.)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-137（3T18m-09）] Antioxidant Metabolism in Uric Acid Synthesis in the Eternal Life Model Organism, Reticulitermes speratus.

^〇Yuki Kajiwara¹, Hirotaka Kimura¹, Yuki Nakasuji¹, Eisuke Tasaki², Yoshihito Iuchi¹ (1.Department of Biological Chemistry, Graduate School of Science and Technology for Innovation, Yamaguchi University, 2.Faculty of Science)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-138（1T08a-07）] Inhibition of xCT,cystine/glutamate transporter, supresses chronic inflammation in a mouse model of inflammatory bowel disease

^〇Hideya Iwaki¹, Hiroki Sekine¹, Shohei Murakami¹, Nobufumi Kato³, Hiroshi Kitamura⁴, Fan-Yan WE⁵, Shinji Fukuda⁶, Tomoyoshi Soga⁶, Yoichi Kakuta², Atsushi Masamune², Hozumi Motohashi¹ (1.Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, 2.Division of Gastroenterology, Tohoku University, 3.Division of Advanced Surgical Science and Technology, Tohoku University, 4.Division of Microbiology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, 5.Department of Modomics Biology and Medicine, Institute of Development, Aging and Cancer, Tohoku University, 6.Institute for Advanced Biosciences, Keio University)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-139（1T08a-01）] Identification and characterization of D-amino acid transporter from lactic acid bacteria

^〇Koichiro Aoki¹, Hisashi Hemmi¹, Tomokazu Ito¹ (Nagoya University Graduate School of Bioagricultural Sciences Department of Applied Biosciences)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-140] Analysis of sphingosine 1-phosphate transport mechanism by using the SPNS2 mutants

Shoko Nishi-Kawasaki^1,2, Ryosuke Nakashima^1,2, ^〇Tsuyoshi Nishi^1,2 (1.Department of Biomolecular Science and Regulation, SANKEN, Osaka University, 2.AMED-CREST)

The 95th Annual Meeting of the Japanese Biochemical Society

[3P-141] Gastric cancer cell invasion is regulated through Integrin beta5-FARP1-CDC42 axis and Integrin beta5 inhibitor can suppress the invasion.

^〇Tatsuhiko Furukawa¹, Masatatsu Yamamoto², Kohichi Kawahara², Kentaro Minami³ (1.Dept Pathology Kagoshima Univ Grad shc Med Dent , 2.Dept Molecular Oncology Kagoshima Univ Grad shc Med Dent , 3.Dep of Pharmacy, Univ. of Miyazaki Hospital)

The 95th Annual Meeting of the Japanese Biochemical Society