The Japanese Biochemical Society

[1P-004] BRCC36 associates with FLT3-ITD to regulate its protein stability and intracellular signaling in acute myeloid leukemia

Jianwei Liu1, Tomoya Isaji1, Sachiko Komatsu2, Yuhan Sun1, Xing Xu1, Tomohiko Fukuda1, Tsutomu Fujimura2, Shinichiro Takahashi3, Jianguo Gu1 (1.Institute of Molecular Biomembrane and Glycobiology, Tohoku Medical and Pharmaceutical University, 2.Division of Bioanalytical Chemistry, Tohoku Medical and Pharmaceutical University., 3.Division of Laboratory Medicine, Faculty of Medicine, Tohoku Medical and Pharmaceutical University.)

キーテクノロジー:TurboID

FLT3、Ubiquitination、BRCC36

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