[1P-150] The ubiquitin ligase RNF181 plays a pivotal role in sustaining the mammalian proteasome activity under proteasome impairment

^〇Jun Kishiki¹, Eiichi Hashimoto¹, Shoshiro Hirayama¹, Hidetaka Kosako², Jun Hamazaki¹, Shigeo Murata¹ (1.Laboratory of Protein Metabolism, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., 2.Division of Cell Signaling, Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan.)

キーテクノロジー：プロテアソーム機能制御

プロテアソーム、E3リガーゼ、ユビキチン