The Japanese Biochemical Society

[1P-180] Protonation states of Asp residues in the broad substrate recognition of human MTH1

Teruya Nakamura1, Yukari Koga-Ogawa2, Kana Fujimiya3, Mami Chirifu1, Masataka Goto3, Shinji Ikemizu1, Yusaku Nakabeppu4, Yuriko Yamagata1,5 (1.Graduate School of Pharmaceutical Sciences, Kumamoto University, 2.Faculty of Health Sciences, Nihon Institute of Medical Science, 3.School of Pharmacy, Kumamoto University, 4.Medical Institute of Bioregulation, Kyushu University, 5.Shokei University and Shokei University Junior College)

キーテクノロジー:X線結晶構造解析

酵素、基質認識、Asp残基、プロトン化状態

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