The Japanese Biochemical Society

[1P-286] Golgi retention and oncogenic KIT signaling via PLCγ2-PKD2-PI4KIIIβ activation in gastrointestinal stromal tumor cells

Yuuki Obata1, Kazuo Kurokawa2, Takuro Tojima2, Miyuki Natsume1,3, Isamu Shiina3, Tsuyoshi Takahashi4, Ryo Abe5, Akihiko Nakano2, Toshiro Nishida6,7 (1.Intracell. Traffic & Oncol., NCCRI, 2.Center for Adv. Photonics, RIKEN, 3.Grad. Sch. of Sci., Tokyo Univ. of Sci., 4.Dept. of Surg., Grad. Sch. of Med., Osaka Univ., 5.Tokyo Univ. of Sci., 6.NCC Hospital, 7.Osaka Hospital)

キーテクノロジー:免疫蛍光染色

レセプターチロシンキナーゼ、局在異常、ゴルジ体/TGN、消化管間質細胞腫

yuobata@ncc.go.jp

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