The Japanese Biochemical Society

[1P-395] Phip deficiency leads to the expansion of hematopoietic stem/progenitor cells and splenomegaly upon aging

Yuko Kato1, Takako Yokomizo2, Goro Sashida3, Atsushi Iwama2, Satoru Miyagi4 (1.Department of Life Science, Faculty of Medicine, Shimane University, 2.Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo , 3.International Research Center for Medical Sciences, Kumamoto University, 4.Department of Biochemistry, Faculty of Medicine, Shimane University)

キーテクノロジー:Gene Targeting

Hematopoietic stem cell、PHF6、chromatin

miyagi@med.shimane-u.ac.jp

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