The Japanese Biochemical Society

[1P-535] Evaluation of the efficacy of RFFL antisense oligos in improving the function of cystic fibrosis-associated CFTR mutants.

Daichi Hinata1, Yukari Fukuda1, Ryosuke Fukuda1, Yuuya Kasahara2, Satoshi Obika3, Tokuyuki Yoshida4, Takao Inoue4, Tsukasa Okiyoneda1 (1.Department of Biomedical Sciences, School of Biological and Environmental Sciences, Kwansei Gakuin University, 2.National Institute of Biomedical Innovation,Health and Nutrition, 3.Graduate School of Pharmaceutical Sciences, Osaka University, 4.Division of Molecular Target and Gene Therapy Products, National Institute of Health Sciences)

キーテクノロジー:ASOによるRFFL機能阻害

嚢胞性線維症(CF)、ASO、E3 ligase、CFTR、RFFL

daichi.hinata@kwansei.ac.jp

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