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[1T02a-02(2P-002)] Modulation of NOTCH2-ligand binding by O-glucose glycan on the ligand binding domain

Wataru Saiki1, Yuuki Kurebayashi2, Kunika Tonooka2, Yohei Tsukamoto1, Yuka Sakuma1, Atsuki Uchida1, Yusuke Urata1, Akira Minami2, Tadanobu Takahashi2, Yuji Kondo1,3, Tetsuya Okajima1,3, Hideyuki Takeuchi2 (1.Department of Molecular Biochemistry, Nagoya University Graduate School of Medicine, 2.Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka , 3.Institute for Glyco-core Research, Nagoya University)

キーテクノロジー:フローサイトメトリー

Notchシグナル、EGFドメイン、O-グルコース糖鎖

saiki.wataru.n6@s.mail.nagoya-u.ac.jp

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