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[1T06a-11(1P-172)] Characterization of regulation mechanism of intrinsically weak affinity interactions of a multi-specific ligand PRELP through ECM localization

Hirofumi Kosuge1, Makoto Nakakido1,2, Susana, de Vega3, Satoru Nagatoishi4, Tetsuya Fukuda5, Yasuhiko Bando5, Shin-ichi Ohnuma6, Kouhei Tsumoto1,2,3,4 (1.Dept. of Chem. Biotech., Sch. of Eng., Univ. of Tokyo, 2.Dept. of Bioeng., Sch. of Eng., Univ. of Tokyo, 3.Inst. of Med. Sci., Univ. of Tokyo, 4.Med. Dev. Dev. Reg. Res. Center, Sch. of Eng., Univ. of Tokyo, 5.Biosys Technologies, 6.Inst. of Ophthalmology, Univ. College London)

キーテクノロジー:免疫細胞染色

PRELP、SLRPs、多重特異的相互作用、細胞増殖抑制、細胞外マトリクス

h-kosuge@g.ecc.u-tokyo.ac.jp

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