Modulation of NOTCH2-ligand binding by <I>O</I>-glucose glycan on the ligand binding domain

Wataru Saiki

[2P-002(1T02a-02)] Modulation of NOTCH2-ligand binding by O-glucose glycan on the ligand binding domain

^〇Wataru Saiki¹, Yuuki Kurebayashi², Kunika Tonooka², Yohei Tsukamoto¹, Yuka Sakuma¹, Atsuki Uchida¹, Yusuke Urata¹, Akira Minami², Tadanobu Takahashi², Yuji Kondo^1,3, Tetsuya Okajima^1,3, Hideyuki Takeuchi² (1.Department of Molecular Biochemistry, Nagoya University Graduate School of Medicine, 2.Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka , 3.Institute for Glyco-core Research, Nagoya University)

キーテクノロジー：フローサイトメトリー

Notchシグナル、EGFドメイン、O-グルコース糖鎖

saiki.wataru.n6@s.mail.nagoya-u.ac.jp

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The 96th Annual Meeting of the Japanese Biochemical Society

[2P-002(1T02a-02)] Modulation of NOTCH2-ligand binding by O-glucose glycan on the ligand binding domain

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