Elucidation of tissue-specific metabolic mechanisms during chimeric antigen receptor T- cell therapy.

Ari Itoh-Nakadai

[2P-215] Elucidation of tissue-specific metabolic mechanisms during chimeric antigen receptor T- cell therapy.

^〇Ari Itoh-Nakadai^1,2, Mariko Tomizawa-Murasawa¹, Hiroshi Kajita¹, Nahoko Suzuki¹, Yuriko Sorimachi³, Maiko Kobayashi², Takako Shimizu², Takehisa Matsumoto⁴, Mikako Shirouzu⁴, Keiyo Takubo³, Yoriko Saito¹, Fumihiko Ishikawa¹ (1.Laboratory for Human Disease Models, RIKEN Center for Integrative Medical Sciences, RIKEN, 2.Department of Hygiene and public Health, Graduate School of Medicine, Nippon Medical School,, 3.Department of Stem Cell Biology, Research Institute National Center for Global Health and Medicine, 4.Drug Discovery Structural Biology Platform Unit, RIKEN Program for Drug Development and Medical Technology Platforms, RIKEN)

キーテクノロジー：CAR-T細胞

CAR-T細胞、AML、代謝、OXPHOS、抗腫瘍T細胞

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The 96th Annual Meeting of the Japanese Biochemical Society

[2P-215] Elucidation of tissue-specific metabolic mechanisms during chimeric antigen receptor T- cell therapy.

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