Pioneer transcription factor FOXA and PRDM1 guarantee lineage fidelityby coordinating repressive chromatin state.

Satoshi Matsui

[2P-419(1T12a-09)] Pioneer transcription factor FOXA and PRDM1 guarantee lineage fidelityby coordinating repressive chromatin state.

^〇Satoshi Matsui^1,2, Marissa Granitto^1,2,4, Morgan Buckley^1,2, Joseph Shiley^1,2, Hee-Woong Lim³, Makiko Iwafuchi^1,2,4 (1.Division of Developmental Biology, CCHMC, 2.Center for Stem Cell&Organoid Medicine (CuSTOM), CCHMC, 3.Division of Biomedical Informatics, CCHMC, 4.Department of Pediatrics, University of Cincinnati Collage of Medicine)

キーテクノロジー：ChIP-seq, CRISPR-Cas9

幹細胞、分化、エピジェネティクス、パイオニア転写因子

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The 96th Annual Meeting of the Japanese Biochemical Society

[2P-419(1T12a-09)] Pioneer transcription factor FOXA and PRDM1 guarantee lineage fidelityby coordinating repressive chromatin state.

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