[2P-481(1T14a-06)] Novel therapeutic strategy for breast cancer targeting persistent activation of IRE1 mediated by O-glycosylation

^〇Keiji Uchiyama¹, Tetsuro Yoshimaru¹, Yosuke Matsushita^1,2, Masaya Ono³, Yauso Miyoshi⁴, Mitsunori Sasa⁵, Toyomasa Katagiri^1,2 (1.Division of Genome Medicine, Institute of Advanced Medical Sciences, Tokushima University, 2.National Institute of Biomedical Innovation, Health and Nutrition, 3.National Cancar Center Research Institute, 4.Hyogo Medical University, 5.Tokushima Breast Care Clinic)

キーテクノロジー：生細胞超解像イメージング

がん微小環境、小胞体ストレス、IRE1、O型糖鎖修飾