[2P-540] Ciliary cholesterol dysfunction as an etiology of polycystic kidney

Takeshi Itabashi¹, Kosuke Hosoba², Tomoka Morita¹, Kenji Yamaoka³, Sotai Kimura⁴, Daigo Kobayashi¹, Hiroko Kishi^1,5, Hiroshi Itoh⁴, Hideshi Kawakami⁶, Koichi Hashimoto³, Takashi Yamamoto², ^〇Tatsuo Miyamoto¹ (1.Department of Molecular and Cellular Physiology, Graduate School of Medicine, Yamaguchi University, 2. Graduate School of Integrated Sciences for Life, Hiroshima University, 3.Department of Neurophysiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 4.Department of Molecular Pathology, Graduate School of Medicine, Yamaguchi University,, 5.Department of Environmental Physiology, Faculty of Medicine, Shimane University, 6.Department of Molecular Epidemiology, Research Institute for Radiation Biology and Medicine, Hiroshima University)

キーテクノロジー：ゲノム編集

多発性嚢胞腎、コレステロール、一次繊毛、ゲノム編集