Different involvement of neurodegeneration between homozygous and heterozygous mice in prosaposin gene mutation

Kentaro Gejima

[2P-622] Different involvement of neurodegeneration between homozygous and heterozygous mice in prosaposin gene mutation

^〇Kentaro Gejima¹, Yutaka Oji¹, Ryo Wakamori¹, Taku Hatano¹, Junji Yamaguchi², Ayami Okuzumi¹, Nobutaka Hattori^1,3 (1.Department of Neurology, Juntendo University School of Medicine, 2.Laboratory of Morphology and Image Analysis, Research Support Center, Juntendo University Graduate School of Medicine, 3.Neurodegenerative Disorders Collaborative Laboratory, RIKEN Center for Brain Science)

キーテクノロジー：病態モデルマウス

プロサポシン、パーキンソン病、ライソゾーム病、プルキンエ細胞、酸性セラミダーゼ

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The 96th Annual Meeting of the Japanese Biochemical Society

[2P-622] Different involvement of neurodegeneration between homozygous and heterozygous mice in prosaposin gene mutation

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