[2P-642(1T18a-10)] Combined immunotherapy of chimeric antigen receptor T cells targeting STEAP1 with extracellular matrix-targeted IL-12 for advanced prostate cancer

^〇Koichi Sasaki¹, Bhatia Vipul², Ishihara Jun¹, Lee John K.^2,3,4,5 (1.Department of Bioengineering, Imperial College London, 2.Human Biology Division, Fred Hutchinson Cancer Center, 3.Division of Medical Oncology, University of Washington, 4.Department of Pathology and Laboratory Medicine, University of Washington, 5.Clinical Research Division, Fred Hutchinson Cancer Center)

キーテクノロジー：Chimeric antigen receptor

Cancer immunotherapy、CAR-T cells、Protein engineering、Drug delivery system、Prostate cancer