9:50 AM - 10:10 AM

[2S12m-04] Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals

^〇Uladzimir Barayeu^1,2, Danny Schilling^2,3, Mohammad Eid^2,3, Thamara Nishida Xavier da Silva⁴, Lisa Schlicker^5,6, Nikolina Mitreska⁷, Christopher Zapp^8,9, Frauke Graeter⁸, Aubry K. Miller¹⁰, Reinhard Kappl⁷, Almut Schulze⁵, Jose Pedro Friedmann Angeli⁴, Tobias P. Dick^2,3 (1.Department of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine, Sendai, Japan, 2.Division of Redox Regulation, German Cancer Research Center (DKFZ), Heidelberg, Germany, 3.Faculty of Biosciences, Heidelberg University, Heidelberg, Germany, 4.Rudolf-Virchow-Zentrum - Center for Integrative and Translational Bioimaging, University of Wuerzburg, Wuerzburg, Germany, 5.Division of Tumor Metabolism and Microenvironment, DKFZ, Heidelberg, Germany, 6.Proteomics Core Facility, DKFZ, Heidelberg, Germany, 7.Department of Biophysics, Faculty of Medicine, Center for Integrative Physiology and Molecular Medicine (CIPMM), Homburg, Germany, 8.Molecular Biomechanics, Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany, 9.Institute for Theoretical Physics, Heidelberg University, Heidelberg, Germany, 10.Research Group Cancer Drug Development, DKFZ, Heidelberg, Germany)

キーテクノロジー：mass spectrometry

persulfide、ferroptosis、sulfur、lipid oxidation