09:50 〜 10:10
[2S12m-04] Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals
〇Uladzimir Barayeu1,2 Danny Schilling2,3 Mohammad Eid2,3 Thamara Nishida Xavier da Silva4 LisaSchlicker5,6 Nikolina Mitreska7
ChristopherZapp8,9 Frauke Graeter8 Aubry K.Miller10 Reinhard Kappl7 Almut Schulze5 Jose Pedro Friedmann Angeli4 Tobias P.Dick2,3
(1.Department of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine, Sendai, Japan, 2.Division of Redox Regulation, German Cancer Research Center (DKFZ), Heidelberg, Germany, 3.Faculty of Biosciences, Heidelberg University, Heidelberg, Germany, 4.Rudolf-Virchow-Zentrum - Center for Integrative and Translational Bioimaging, University of Wuerzburg, Wuerzburg, Germany, 5.Division of Tumor Metabolism and Microenvironment, DKFZ, Heidelberg, Germany, 6.Proteomics Core Facility, DKFZ, Heidelberg, Germany, 7.Department of Biophysics, Faculty of Medicine, Center for Integrative Physiology and Molecular Medicine (CIPMM), Homburg, Germany, 8.Molecular Biomechanics, Heidelberg Institute for Theoretical Studies (HITS), Heidelberg, Germany, 9.Institute for Theoretical Physics, Heidelberg University, Heidelberg, Germany, 10.Research Group Cancer Drug Development, DKFZ, Heidelberg, Germany)
キーテクノロジー:mass spectrometry
persulfide、ferroptosis、sulfur、lipid oxidation