NICER: A gene editing approach for correcting heterozygous mutations through multiple nicks-induced interhomolog homologous recombination

Shinichiro Nakada

5:10 PM - 5:30 PM

[2S14e-01] NICER: A gene editing approach for correcting heterozygous mutations through multiple nicks-induced interhomolog homologous recombination

^〇Shinichiro Nakada^1,2, Akiko Tomita², Hiroyuki Sasanuma³, Tomoo Oowa², Yuka Nakazawa⁴, Tomoo Ogi⁴, Mayuko Shimada⁴ (1.Institute for Advanced Co-Creation Studies, Osaka University, 2.Department of Bioregulation and Cellular Response, Graduate School of Medicine, Osaka University, 3.Department of Genome Medicine, Tokyo Metropolitan Institute of Medical Science, 4.Department of Genetics, Research Institute of Environmental Medicine(RIeM) , Nagoya University)

キーテクノロジー：ゲノム編集、次世代シーケンス

ゲノム編集、遺伝子治療、相同組換、CRISPR/Cas、相同染色体間組換

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The 96th Annual Meeting of the Japanese Biochemical Society

[2S14e-01] NICER: A gene editing approach for correcting heterozygous mutations through multiple nicks-induced interhomolog homologous recombination

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