9:30 AM - 9:50 AM

[3S01m-03] Identification of a novel component of "p62 body" formed by liquid-liquid phase separation and elucidation of its significance for degradation by selective autophagy

^〇Hideaki Morishita^1,2, Reo Kurusu², Yuki Fujimoto², Daisuke Noshiro³, Shuhei Takada², Koji Yamano⁴, Hideaki Tanaka⁵, Ritsuko Arai⁶, Shun Kageyama², Tomoko Funakoshi², Satoko Komatsu-Hirota², Hikari Taka⁷, Saiko Kazuno⁷, Yoshiki Miura⁷, Masato Koike⁸, Toshifumi Wakai⁹, Satoshi Waguri⁶, N. Nobuo Noda³, Masaaki Komatsu² (1.Graduate School of Medical Sciences, Kyushu University, 2.Juntendo University Graduate School of Medicine, 3.Institute for Genetic Medicine, Hokkaido University, 4.Medical Research Institute, Tokyo Medical and Dental University, 5.Institute for Protein Research, Osaka University, 6.Fukushima Medical University School of Medicine, 7.Biomedical Research Core Facilities, Juntendo University Graduate School of Medicine, 8.Department of Cell Biology and Neuroscience, Juntendo University Graduate School of Medicine, 9.Niigata University Graduate School of Medical and Dental Sciences)

キーテクノロジー：液滴精製、定量的プロテオミクス

液ー液相分離、選択的オートファジー、ヴォルト、肝細胞がん、p62 body