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[3S04m-04] Potential for novel therapies for cancers with YAP/TAZ activation, focusing on aberrant post-translational modifications of nucleoporins

Satomi Mukai1, Tatushiro Sato1, Yasuhiro Kamei2, Kagayaki Kato2, Emi Mishiro-Sato3,4, Masahiro Aoki4, Kenszo Hiroshima5,6, Yoshitaka Sekido1 (1.Division of Cancer Biology, Aichi Cancer Center Research Institute, 2.Optics and Imaging Facility, Trans-Scale Biology Center, National Institute for Basic Biology, 3.Institute of Transformative Bio-Molecules, Nagoya University, 4.Division of Pathophysiology, Aichi Cancer Center Research Institute, 5.Department of Biochemistry and Genetics, Chiba University Graduate School of Medicine, 6.Department of Pathology, Tokyo Women's Medical University Yachiyo Medical Center)

キーテクノロジー:核輸送動態の解析

O-GlcNAc 修飾、ヌクレオポリン、YAP/TAZ

smukai@aichi-cc.jp

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