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[3S06e-03] Therapeutic antibody reinforced by wedges: Specific peptide conjugation leads to enhanced therapeutic potency and thermal stability

Masato Kiyoshi1, Makoto Nakakido2, Abdur Rafique3, Minoru Tada1, Michihiko Aoyama1, Yosuke Terao4, Satoru Nagatoishi5, Hiroko Shibata1, Teruhiko Ide4, Kouhei Tsumoto2,5, Yuji Ito3, Akiko Ishii-Watabe1 (1.National Institute of Health Sciences, Japan, 2.School of Engineering, The University of Tokyo, 3.Graduate School of Science and Engineering, Kagoshima University, 4.Tosoh Corporation, 5.The Institute of Medical Science, The University of Tokyo)

キーテクノロジー:ペプチドコンジュゲーション

抗体医薬品、ペプチド、抗体薬物複合体、ダイナミクス

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